In addition, studies have found that LAGE3 is a prognostic biomarker associated with levels of immune infiltration in the microenvironment of clear cell renal cell cancer, colorectal cancer, malignant pleural mesothelioma, breast cancer (BC), skin cutaneous melanoma, and papillary thyroid cancer (PTC) (11–16). This evidence concerns the gene LAGE3 and breast carcinoma.