This study is in concordance with Elsayed et al. [19], which was carried on 100 patients with chronic HCV-induced liver disease with early stage of cirrhosis, found a significant improvement at 6 months after DAAs (at SVR 24) in laboratory values (platelet count, albumin, bilirubin, AST, ALT), PVV, APRI score, and PC/SD ratio, with contrast to our results regarding PVD that was not significantly decreased after DAAs (p-value = 0.345). This evidence concerns the gene ALB and liver disorder.