TNF and Stroke: As described in Figure 4, three typical pathways were involved in the mechanism of action of AGNHW against stroke, including the interleukin (IL)-17 signaling pathway, TNF signaling pathway, and the PI3K/AKT signaling pathway, all of which have been reported to participate in the regulation of a variety of biological processes, including cell proliferation [34], apoptosis [35], inflammation [36], and survival growth [34].