Yang et al. reported that miR-199a-5p was sponged to hsa_circ_0060450, releasing target gene SHP2, and showed it suppressed the JAK-STAT signaling pathway triggered by type I interferon (IFN-I) to inhibit macrophage-mediated inflammation in T1DM [30]. This evidence concerns the gene SOAT1 and type 1 diabetes mellitus.