We compared the expression level of HOXC6 across four glioblastoma subtypes (classical, mesenchymal, neural, and proneural) and found that only the proneural subtype had a significant heterogeneity in the expression levels of HOXC6 among four glioblastoma subtypes (p = 0.003, t-test). The gene discussed is HOXC6; the disease is glioblastoma.