Studies have confirmed that S100A2 participates in processes such as cell proliferation and migration in some tumors (Bulk et al., 2009; Wolf et al., 2011) A previous study showed that high expression of S100A2 in patients with non-small cell lung cancer has a worse prognosis (Wang et al., 2005). This evidence concerns the gene S100A2 and non-small cell lung carcinoma.