The aberrant phase transitions within liquid-like droplets lie at the heart of many kinds of diseases, such as TATA box-binding protein (TBP, OMIM#600075) for spinocerebellar ataxia 17 (SCA17, OMIM#607136) (Friedman et al., 2007), FUS (OMIM#137070) for amyotrophic lateral sclerosis 6 (ALS6, OMIM#608030) (Patel et al., 2015), and androgen receptor (AR, OMIM#313700) for spinal and bulbar muscular atrophy (SBMA, OMIM#313200). Here, TBP is linked to spinocerebellar ataxia type 17.