Median CRP level was significantly different among the 3 Hurley groups and increased with the degree of severity. There were significant positive correlations between CRP levels and neutrophil count with modified Hidradenitis Suppurativa Score. CRP was a significant independent predictor for Hurley Stage III. CRP and body mass index were significant independent predictors for severe disease according to modified Hidradenitis Suppurativa Score. The gene discussed is CRP; the disease is hidradenitis.