↓excessive inflammation ↓neutrophils recruitment ↓bacterial burden ↑phagocytosis monocytes and macrophages in CLP sepsis models.↓HMGB1 ↓excessive inflammation ↓neutrophils recruitment in LPS/GalN model↓hepatocyte apoptosis in a dose dependent manner in LPS/GalN model. Here, GAL is linked to Sepsis.