GATA3 and asthma: Besides, miR-144-3p overexpression in bronchial smooth muscle cells only affected GATA3 mRNA, and previous reports have shown that the reduction of GATA3 by SB010 DNAzyme attenuated allergic asthma responses by type 2 helper T-cell (Th2) reduction (32), so in this sense, miR-144-3p may behave as an inhibitor of GATA3 in a similar manner and may even control signaling pathways involved in asthma pathophysiology as observed in silico.