As an example, IMC study of cells within prostatic and bone marrow samples in patients with metastatic prostatic adenocarcinomas has been performed by Malihi et al., who not only confirmed the maintained luminal prostate epithelial cell lineage of tumor cells between samples through the co-expression of EpCAM, PSA and PMSA, but also demonstrated that the level of expression of androgen receptor was higher in metastatic tumor cells than in prostatic ones (37). This evidence concerns the gene AR and neoplasm.