For example, a recent study reported transfer of WT1-TCR-engineered donor T cells into AML patients at high risk of relapse following allogeneic stem cell transplantation, 12/12 treated patients achieved relapse-free survival (13), compared to 54% in a concurrent group of 88 similar high-risk patients, and WT1-TCR-T cells also showed prolonged persistence and maintenance of antigen-specific polyfunctional activity. Here, WT1 is linked to acute myeloid leukemia.