In the analyses of clinical characteristics of patients with T2DM aged between 51 and 60 by the quartiles of LH and FSH (Supplemental Tables 3, 4), patients with the higher level of LH and FSH were more likely to experience significantly higher TC and HDL-C compared with those with the bottom quartile of LH and FSH. This evidence concerns the gene BRD2 and type 2 diabetes mellitus.