S100A6 and cancer: GSEA results showed that S100A6 overexpression was associated with cancer- and glycometabolism-related pathways such as pathway in cancer, p53 signaling pathway, Notch signaling pathway, and cell cycle, as well as in glycan biosynthesis, pentose phosphate pathway, sugar metabolism, galactose metabolism, and sucrose metabolism, demonstrating that S100A6 was possibly implicated in cancer growth and glucose metabolism (Figure 6).