Two cousins with hyposmia (cases 24-25) carried an ANOS1 c.171_181del (p.Gln57fs*) variant inherited from their mothers, and bilateral inguinal cryptorchidism developed after 6 years of age in a proband, but in his cousin right-sided inguinal cryptorchidism and micropenia presented at 1 year of age and he had orchidopexy at 5 and 9 years without an effect. The gene discussed is ANOS1; the disease is cryptorchidism.