It has likewise been reported that rTMS applied to both the left and right DLPFC can be administered in the effective treatment of depression and can improve serum neuron-specific enolase (NSE) and brain-derived neurotrophic factor (BDNF) levels as well as temporal perception in neurologic patients, causing an overall protective effect on neurological function (34, 37, 38). This evidence concerns the gene BDNF and depressive symptom measurement.