ACE2 and COVID-19: Thus, it is not surprising that pregnant women constitute a potentially vulnerable population in the COVID-19 pandemic, with initial results indicating that the clinical response of pregnant women to COVID-19 could be related to physiological changes in expression levels of ACE2 and reduced sensitivity to Ang II (Anton et al., 2008; Gilbert et al., 2008; Liu D. et al., 2020; Mendoza et al., 2020).