Our previous studies demonstrated that TGF-β1-induced proliferation and differentiation of fibroblasts could be inhibited by miR-130a-3p in the MLG2908 cell line, but whether miR-130a-3p can inhibit the progression of PF in vivo, especially in different phases of PF has not been established (Liu et al., 2021). This evidence concerns the gene TGFB1 and pemphigus foliaceus.