TGFB1 and pemphigus foliaceus: Among the various cytokines participating in the process of the PF mouse model (Barkauskas and Noble 2014), TGF-β1 is currently the most potent profibrogenic cytokines, which can lead to EMT, provoke fibroblast proliferation, promote myofibroblast formation, and result in ECM deposition (Kim et al., 2018; Lodyga and Hinz 2020).