Combined with the results of in vivo experiments, it is suggested that QGHXR can improve the imbalance of the LXRα-LPCAT3 pathway and prevent further development of ERS, which is mainly related to PERK-eIF2α and IRE1α, and a relatively small relationship with the ATF6 pathway (Figure 5). This evidence concerns the gene ATF6 and amelogenesis imperfecta type 1G.