SCN2A and epilepsy: At present, voltage-gated sodium channel genes such as SCN1A, SCN2A, SCN3A, and SCN8A were reported to be causative genes of epilepsy (Ademuwagun et al., 2021), among them SCN2A has been reported to be the second most common, next only to SCN1A, the first reported causative gene for epilepsy (Heyne et al., 2019).