AUTS2 and autism spectrum disorder due to AUTS2 deficiency: The utilization of patient AUTS2 variant iPSCs to create assembloids and brain region specific organoids, such as hippocampal and cerebellar organoids, will provide invaluable tools to understand mechanisms underlying AUTS2 syndrome at multiple levels of analysis including molecular, cellular, and functional levels, as well as provide a novel screening platform for developing therapeutics.