ADIPOQ and ovarian carcinoma: Lastly, the results of univariate and multivariate logistic regression analyses showed that abnormal ADPN, D-D, hs-CRP, IL-6, CA125, and HE4 levels were related risk factors affecting the development of ovarian cancer, and lowered ADPN level and raised D-D, hs-CRP, IL-6, CA125, and HE4 levels were independent risk factors affecting the development of ovarian cancer.