The effects of immRNA were also assessed in human triple‐negative basal‐like breast cancer (TNBC) CA1a cells, which is a progressively aggressive and metastatic derivative of MCF10A cells, with the same doses of immRNA‐loaded RBCEVs, yielding a similar up‐regulation of RIG‐I related genes. The gene discussed is RIGI; the disease is breast carcinoma.