qPCR analysis of the dissociated tumour cells clearly showed decreased level of miR‐125b and increased levels of Ddx58, Mda5, Irf7, Ifnb, Rsad2, and Isg56 in the tumours treated with 3p‐125b‐ASO‐loaded RBCEVs as compared to NC‐RNA‐loaded RBCEVs (Figure 5c‐d). This evidence concerns the gene IFNB1 and neoplasm.