qPCR analysis of the dissociated tumour cells revealed that the delivery of immRNA‐loaded RBCEVs led to the up‐regulation of Ddx58, Mda5, Mavs, Irf3, Irf7, Ifnb, Rsad2, and Isg56 in the tumours (Figure 4c). This evidence concerns the gene IRF7 and neoplasm.