NEDD4L and myocardial infarction: In addition, in a study of simulating myocardial infarction in Nedd4L-C2-KO mice, Minegishi et al. found that within 6 weeks after myocardial infarction in Nedd4L-C2-KO mice, the PR interval was significantly shortened compared with wild-type MI mice, QT interval and QTc was prolonged, T peak/T wave end interval showed an enhancement as well [113].