NEFL and Mental deterioration: NfL values in the range from 14 to 19 pg/ml have been suggested as cut-off values for a higher risk of cognitive decline (MoCA) (Aamodt et al. 2021; Lin et al. 2019), but likely cohort-related age-adjusted NfL levels are more reliable (Buhmann et al. 2022; Ma et al. 2021).