Consequently, an anti-CD160 mAb with anti-angiogenic properties has been characterized, its injection promoting regression of the tumor vasculature and normalization of the remaining vessels in B16 melanoma-bearing mice, but also inhibition of ocular neovascularization in rabbit cornea or in a mouse model of oxygen-induced retinopathy [27, 28]. The gene discussed is CD160; the disease is neoplasm.