In order to determine if CD160-GPI processing to the cell plasma membrane might be induced following activation, SKMEL5 and WM1361 cells were incubated in the presence of IFN\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\gamma$$\end{document}γ, a cytokine previously described as enhancing PD-L1 expression on melanoma cells [22, 23]. The gene discussed is CD160; the disease is melanoma.