In addition, participants with CKD had a 1.56–1.79 fold increased odds of carrying NLRP3 rs12239046 CT/TT, NLRP3 rs10925025 AG/GG, NLRP3 rs1539019 CA/AA, NLRP3 rs10925026 CA/AA, and NLRP3 rs10157379 CT/TT genotypes compared to controls. The gene discussed is NLRP3; the disease is chronic kidney disease.