Due to the restricted expression of XCR1 on cDC1s, and its endocytic nature, XCR1 represents a highly attractive target for the delivery of tumor antigens in vivo, and to induce CD8+ T cell responses.13–15 We chose to use its ligand, XCL1, as a tumor antigen delivery moiety.14 16 17. The gene discussed is XCL1; the disease is neoplasm.