In cores-rods myopathy and MmD mutations in a mixture of different genes have been reported including RYR1 [5], SELENON, MYH2, MYH7, TTN, CCDC78, UNC45B, ACTN2, and MEGF10, NEB, ACTA1, KBTBD13, CFL2, TRIP4, and TNNT1[8]. Here, RYR1 is linked to myopathy.