The commonly used radionuclides for detecting PCa bone metastasis lesions are radionuclide fluorine-18-fluorodeoxyglucose(18F-FDG), gallium 68 prostate-specific membrane antigen (68 Ga-PSMA) and fluorine 18 sodium fluoride(18F-NaF). The gene discussed is FOLH1; the disease is posterior cortical atrophy.