For example, Kobayashi and Yamamoto as well as Morgan and Liu [65, 66] described the role of ROS in enhancing tumor cell survival by activating the transcription factors NF-κB and NRF2, leading to the upregulation of antioxidant proteins responsible for rescuing cancer cells from the drastic effect of ROS production. The gene discussed is NFKB1; the disease is neoplasm.