The MCP sT1w/T2w ratio values were significantly lower in patients with MSA-C than those in patients with SCA3 and SCA6 and controls (0.07 ± 0.06 vs. 0.17 ± 0.03, 0.18 ± 0.03, and 0.19 ± 0.03, respectively; p < 0.001) (Fig 3). The gene discussed is CACNA1A; the disease is multiple system atrophy, cerebellar type.