–34 In our experiments, statistical significant differences were observed for the proteins LF (0.7-fold change, P = 0.004), S100A6 (1.4-fold change, P = 0.03) and MT1A (1.9-fold change, P = 0.006), when comparing AMD patients and control subjects (see Figs. 2A, 2B, 2F). Here, S100A6 is linked to age-related macular degeneration.