Based on microarray analyses, we found that known oncogenes in GC, including ErbB2, Cdkn2a, MAX, TERT, K-Ras, N-Ras, Cyclin E, c-Met and FGFR2, were upregulated at 14 months of age, whereas the tumor suppressors P53, CDH1 and APC were downregulated (Fig. 2, a). The gene discussed is CDKN2A; the disease is gastric cancer.