TNF-α was a pleiotropic inflammatory cytokine that promoted the proinflammatory response in coronary atherosclerosis and was also risk factor for coronary artery disease, and circulating TNF-α levels were related to increased risks of stable angina pectoris, unstable angina, and recurrent myocardial infarction [9–11]. This evidence concerns the gene TNF and myocardial infarction.