Meanwhile, a previous study investigated serum VEGF level response after TACE with different embolic agents in patients with HCC and reported cTACE group had a more extraordinary rise in the circulating plasma levels of VEGF compared to the DEB-TACE group for 24-hour post-TACE and during the 4-week follow-up (114% vs. 164%, p=0.01; 123% vs. 170%, p=0.03) (33). The gene discussed is VEGFA; the disease is hepatocellular carcinoma.