In the GSE87211 cohort, the multivariate analysis was not performed because the event number was too limited (28 events out of 203 cases) and there were at least seven required variables for Cox regression (age, invasion depth, lymph node metastasis, metastasis, recurrence, KRAS mutations, and score level) (46). This evidence concerns the gene KRAS and metastatic malignant neoplasm in the lymph nodes.