Using breast cancer human cell lines MDA-MB-468 and SKBR3 as in vitro models, the authors have shown that the EGFR-imprinted fluorescein-labelled nanoMIPs with size 150–200 nm specifically recognized MDA-MB-468 EGFR-positive cells, but not SKBR3 EGFR-negative cells. This evidence concerns the gene EGFR and breast cancer.