The anti-inflammatory effect of CM is a consequence of the reduction of NF-κB, cyclooxygenase 2 (COX2) and tumour necrosis factor-α (TNF-α).6,7In vitro studies have shown that the cancer cells are not killed unless they are exposed to 5–50 μM of CM.8,9 There are several methods for CM detection, such as HPLC,10–12 UV fluorescence13 and electrochemical methods.14–16 Electrochemical sensors possess high sensitivity, portability, rapid measurement, simplicity and need a small quantity of sample.17,18 Commercial applications confirm the attractive advantages of these biosensors.19,20. This evidence concerns the gene PTGS2 and cancer.