BCL2 and rheumatoid arthritis: It is suggested that quercetin, plays a role in counteracting RA inflammation, and thus may be reasonably proposed as an adjuvant drug for RA treatment.61 Xiao et al. collected synovial tissue samples from patients with RA and proved that quercetin can affect the apoptosis of RAFLS by regulating the expression of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax).