Genistein in combination with β-lapachone, a quinone from Tabebuia avellanedae having 3,4-dihydro-2H-benzo [h]chromene-5,6-dione structure induced apoptosis in prostate cancer through synergistic activation of caspase 3 and NAD(P)H:quinone oxidoreductase (NQO1) dependent pathways respectively (Diaka et al., 2004). The gene discussed is NQO1; the disease is prostate cancer.