The numbers of IL-22R1+ intermediate monocytes were negatively correlated with IL-6 (r=-0.6239, p<0.05), IFN-α (r=-0.7000, p<0.05) and CRP concentrations (r=0.5810, p<0.05) in non-severe infections, whereas they were positively correlated with creatinine levels (r=0.5989, p<0.05) in severe cases (Figure 6B). The gene discussed is CRP; the disease is infection.