Next, we detected the expression levels of SIRT7 in pancreatic cell lines and found that the expression of SIRT7 was higher in cancer cells (AsPC-1, BxPC-3, PANC-1, MiaPaCa-2, CFPAC-1) than in normal ductal epithelial cell (hTERT-HPNE) (Fig. 1D). This evidence concerns the gene SIRT7 and cancer.