For example, SAT1, which has been consistently reported to be significantly down-regulated in the suicide brain [16, 20, 24], was found to be increased in living bipolar subjects with suicidal ideation [27], and in two groups of post-mortem blood from all-male suicide completers with mixed diagnoses (schizophrenia, bipolar, and MDD) [26, 35]. The gene discussed is SAT1; the disease is major depressive disorder.