Therefore in this study, we determined the DNA methylation status at CpG dinucleotides of DAPK1, RASSF1, p16INK4, p14ARF, RIZ1 and SOCS1 in concert with disease progression, imatinib response and overall survival in chronic myelogenous leukaemia. Here, RASSF1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.