A total of six genes including apoptosis related genes (DAPK1 and RIZ1), cell cycle regulating genes (p16INK4A, RASSF1A and p14ARF) and Suppressor of Cytokine Signaling (SOCS1) gene were analysed for promoter CpG dinucleotide methylation in white blood cell DNA from 150 CML patients in different clinical stages of the disease and in matched healthy control subjects by MS-PCR (agarose gel pictures in Fig. 1 of supplementary data). Here, PRDM2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.