Our study found seven downstream factors that may be associated with chemoresistance, LTF, SOD2, STAT1, CDKN2A, CD81, RAC1, and NDRG1 and five factors that may be associated with tumor development, CCN1, DCTN3, MUC1, H1-5, and SLC1A5. This evidence concerns the gene H1-5 and neoplasm.