Comprehensive genome analysis is one useful tool to identify variations of various oncogenes and tumor-suppressor genes, particularly in those genes that code for chromatin remodeling factors (Centore et al. 2020; Goswami et al. 2020; Mao et al. 2013; Mathur 2018; Wei et al. 2014; Ye et al. 2014) One of such genes is ARID1A. However, the variation rate of ARID1A in CRC is low, Jones et al. (Jones et al. 2012) reported 10%, and Kim et al. (49) did not find variations. Here, ARID1A is linked to colorectal carcinoma.