H&E and Plin2 staining of p21 liver sections revealed that, in contrast to the severe microvesicular steatosis seen in Hmgcs2-KO mice at suckling, the livers of Hmgcs2-KO early-wean mice exhibited a significant reduction in lipid accumulation, making their phenotype comparable to those of WT mice (Figure 3F). This evidence concerns the gene PLIN2 and steatosis.