The ELISA kits showed that the concentrations of M1 macrophage-specific cytokines IL-6 and IL-8 were lower whereas the concentrations of M2 macrophage-specific cytokines IL-10 and CXCL13 were higher in T2DM-PTB mice than those in the Sham-PTB mice (Figure 5(a)). This evidence concerns the gene IL10 and type 2 diabetes mellitus.