Moreover, we observed that the expression of the M1 macrophage marker CD86 was decreased whereas the M2 marker CD206 was increased in tissues of T2DM-PTB mice (Figure 5(b)), indicating that T2DM might promote the phenotype transition from M1 to M2 in murine lung tissues to enhance the susceptibility to PTB. The gene discussed is MRC1; the disease is type 2 diabetes mellitus.