Moreover, we found that only one patient out of three with respiratory anti‐IFN‐α NAB had auto‐Abs in paired serum sample (33.3%, n = 1/3), supporting an earlier report showing COVID‐19 patients with serum anti‐IFN‐I NAB can have these antibodies in the respiratory tract [16]. The gene discussed is DDX41; the disease is COVID-19.